Nerolidol

Nerolidol is a sesquiterpene alcohol with a woody aroma that Wikipedia likens to fresh bark, set against a floral background. It occurs in neroli, ginger, jasmine, lavender, tea tree, lemongrass and cannabis, and its richest natural sources include cabreuva oil and Dalbergia parviflora oil. It comes in two geometric forms, cis and trans, and most commercial uses rely on a mixture. The FDA permits it as a food flavoring, and it is common in perfumes, shampoos and household cleaners.

Nerolidol is one of the terpenoids Russo reviewed in his influential 2011 paper on cannabis "entourage effects", but Leafly's strain terpene listings do not track it, and none of the strains in this guide lists it as a main terpene. A 2016 review in Molecules compiles a broad set of laboratory and animal findings — antimicrobial, anti-biofilm, antioxidant, antiparasitic, insecticidal, anti-inflammatory and anti-nociceptive activity — and notes its use as a skin-penetration enhancer, which helps other ingredients cross the skin in topical products. Most of this work has not been tested in people.

PubChem lists nerolidol's boiling point at about 275–277 °C, among the highest of the terpenes in this guide.